Catnip Herb – Some Useful Advanced Information
What Is Catnip?
This plant’s scientific name is Nepeta cataria L.
Catmint is one of the most prevalent names for catnip.
Catnip, a perennial plant native to Europe, has spread to the northeastern United States and Canada. The plant grows to about 1 m in height and has dark green, oval-toothed leaves. The plant’s medicinal benefits are found in its dried leaves and white blossoming tips.
This term’s scientific name (s)
Nepeta cataria L. is a plant in the Lamiaceae family (mint family)
Noun Form (s).
There are several other names for catnip, including cat herb, catnip, and catnip.
An ethnobotanical application.
They may be used as a flavouring element in a broad range of cuisines, from soup to stew to different patent drinks and fruit-based liqueurs. The first proof may be found in 1735. It has been stated that catnip leaves and blossoms are used in herbal cocktails. The plant was also used to treat gastrointestinal spasms and indigestion as a diaphoretic, sedative, and hunger stimulant. In addition to diarrhoea and colic, the plant has been used to cure colds and even cancer. Catnip tea was traditionally used to treat uneasiness, stomach issues, rashes, and colds in Appalachia. Dried leaves were smoked to treat respiratory ailments, and a poultice was applied to the afflicted region. In the early 1900s, flowers and leaves were used to postpone menstruation. Catnip was smoked in the 1960s because of its euphoric effects, according to mythology.
Catnip has been reported to contain around 20 distinct compounds, the concentration of which varies dramatically according to the blooming season and location. The plant contains various sesquiterpenes and monoterpenes, and nepetalactone and beta-caryophyllenes have been discovered using gas chromatography and nuclear magnetic resonance spectroscopy.
Nepetalactone, like valerian’s valepotriates, may have an important cat-suppressive action. The majority of the crucial components in catnip essential oil have been identified as citronellyl acetate and citronellol. It also includes camphor and thymol, as well as other chemicals, including carvacrol and nerol.
Anxiety-Reducing Qualities
According to studies, acute and repeated treatment of apolar or polar catnip extracts (48 mg/kg/day) for seven days showed antidepressant, antianxiety, and motor benefits in mice. A well-balanced diet reduced the amount of time a patient remained immobile. These findings were analogous to those obtained in mice treated with the antidepressant fluoxetine; the apolar extract reduced locomotor activity, rising frequency, and immobility length in the outside test. The behavioural despair test revealed that mice given the apo land extract had a shorter immobility period. Furthermore, the apolar extract shortened the time it needed for the first immobilization. According to the study’s findings, a catnip-enriched diet and apolar extract may have antidepressant properties. Male rats fed diets enriched with 10% N. cataria leaves for four hours showed antidepressant effects.
Cancer
In vitro testing
In an in vitro study, flavonoids extracted from N. cataria L. were utilized to treat the A549 non-small cell lung cancer cell line. The anticancer impact increased owing to increased apoptosis and necrosis rates in A549 cells as flavonoid concentration rose. VEGFR and PI3K mRNA levels in A549 cells were lowered in the treatment group, whereas PTEN levels rose. AKT, cyclin B1, and Bcl-2 levels decreased as PI3K protein levels increased. These findings suggest flavonoid extracts from N. cataria L. may prevent lung cancer by affecting the PTEN/PI3K/AKT pathway.
Anti-insect spray
In vitro and animal studies.
Catnip nepetalactone and iridoids have been studied for their insecticide and herbicide capabilities. Catnip oil has been tested in the field in the United States for its capacity to repel mosquitoes, black flies, stable flies, and deer ticks (Bernier 2005, Feaster 2009). The attraction inhibition of diethyltoluamide is more significant (DEET). Catnip oil components were more efficient in vitro than control at repelling yellow fever mosquitoes (Aedes aegypti L.). When it came to Chauhan in 2005, houseflies, stable flies, and filth flies were efficiently repelled at dosages of 2 mg and 20 mg of catnip. Zhu is the owner of the year 2009. Catnip oil-treated filter paper and wax-based catnip pellets (32 mg per pellet) applied to waste areas of cow pastures both repelled houseflies. Zhu (2010), p. Another research used three different doses of catnip oil to assess its repellent impact on predators (0.2, 2 and 20 mg). Catnip oil was shown to be more effective than DEET at repelling stable insects off a person’s body, with the most substantial amount providing the best protection. A few eggs were laid on cloths treated with 100 mg catnip oil for six hours, indicating an egg-laying deterrent effect. In the study’s outdoor testing, 15% and 30% of catnip oil doses were used to repel stable flies. The capacity of fly oviposition to persist in oviposition cups was demonstrated to be substantially decreased by 500 mg of encapsulated catnip oil. Catnip oil capsules reduced the number of eggs deposited on stable flies’ larval substrate by 85% and more than 98%, respectively. Zhu’s year has arrived. In a lab environment, a 20 mg catnip oil dose repelled horn flies for six hours. Cattle effectively repelled horn flies when treated with 15% catnip oil.
Interactions
Rabbits were fed catnip N. cataria (CNC) and Rhizoma coptidis (RC) orally. CNC absorbed and released berberine, an alkaloid found in Rhizoma coptidis, more readily. The bioavailability of coptisine, palmatine, and epiberberine was lowered. CNC may also lower Epiberberine levels in the blood. Because CNC microparticles can adsorb alkaloids and extend their retention in the small intestine, various alkaloids may have different effects.
The conjunctiva on the upper and lower eyelids inflamed within 24 hours of using 0.1 ml catnip oil. Rabbits were also given 0.5 mL of undiluted catnip oil for 14 days of investigation. From day 3 to day 4, all animals developed redness throughout the assessment period.
Toxicology
According to a recent study, the lethal dose of catnip oil is 1,300 mg/kg intraperitoneally.
Duke University was founded in 2002. Catnip abuse did not generally result in serious physical consequences. However, mild symptoms such as a headache and fatigue have been reported. If a significant amount of tea is taken in excess, it may produce vomiting. Research that covered acute oral and dermal toxicities and primary sensitization looked at the effects of toxins on the skin, eyes, and dermis in mice, rats, and rabbits. For 14 days, a daily dosage of 1,000 to 10,000 mg/kg catnip oil was administered orally. There were no toxicities at doses ranging from 1,000 to 2,150 mg/kg, except for one fatality. A dosage of 4,640 mg/kg or above resulted in a 100% fatality rate. Acute inhalation tests in mice exposed for 2 hours, a topical study in The therapeutic dosage of catnip has never been investigated. A usual sedative dosage is 4 grammes of the dried plant, typically consumed as a tea. An insect repellent cream with 15% essential oil was used. 5,000 mg/kg was applied to the shaved backs of rats, and Catnip oil applied to rabbits’ upper and lower eyelids for 14 days had no negative influence on the animals’ eyes.
Species Data
N. cataria leaf supplementation in male rats’ meals for four hours enhanced their sexual behaviour and performance, as demonstrated by a decrease in ascents preceding ejaculatory ascents and an increase in the frequency of apomorphine-induced penile erections. N. cataria improves the apomorphine-induced penile erection, indicating that the active ingredients contain dopaminergic characteristics.
Catnip dose has never been studied in a therapeutic setting. A typical sedative dosage is 4 grammes of the dry herb, commonly taken as a tea. Insect repellent lotion containing 15% essential oil has been utilized.
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